GO-PROMTO ILLUMINATES PROTEIN MEMBRANE TOPOLOGIES OF GLYCAN BIOSYNTHETIC ENZYMES IN THE GOLGI APPARATUS OF LIVING TISSUES.

GO-PROMTO illuminates protein membrane topologies of glycan biosynthetic enzymes in the Golgi apparatus of living tissues.

The Golgi apparatus is the main site of glycan biosynthesis in eukaryotes.Better understanding of the membrane topology of the proteins and enzymes involved can impart new mechanistic insights into these processes.Publically available bioinformatic tools provide highly variable predictions of membrane topologies for given proteins.Therefore we devi

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StAGE: Stellar Archaeology-driven Galaxy Evolution

We build a semiempirical framework of galaxy evolution (dubbed StAGE ) firmly grounded on stellar archaeology.The latter provides data-driven prescriptions that, on a population statistical ground, allow us to define the age and the star formation history for the progenitors of quiescent galaxies (QGs).We exploit StAGE to compute the cosmic star fo

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